Integration model: iCluster
Dependent variable: PHF1
Sense check variable: PHF1
Clinical covariates: PHF1, amyloid, pTau, AD,
Braak
Correlation threshold: 0.4
Disease ID (Open target database): MONDO_0004975
Chosen clusters: C2-C1 Enrichment
database: Reactome_2016
Number of multi-omics clusters: 2
table1::table1(~. | cluster, data=metadata[,c(covariates,"cluster")])| C1 (N=12) |
C2 (N=12) |
Overall (N=24) |
|
|---|---|---|---|
| PHF1 | |||
| Mean (SD) | 0.521 (0.877) | 1.59 (1.18) | 1.08 (1.16) |
| Median [Min, Max] | 0.0180 [0.000519, 2.66] | 1.74 [0.00114, 3.57] | 0.502 [0.000519, 3.57] |
| Missing | 1 (8.3%) | 0 (0%) | 1 (4.2%) |
| diagnosis | |||
| Control | 3 (25.0%) | 4 (33.3%) | 7 (29.2%) |
| AD | 9 (75.0%) | 8 (66.7%) | 17 (70.8%) |
Weights here represent the posterior probability of features in the multi-omics clustering model
## $`1`
##
## $`2`
##
## $`3`
## $`1`
##
## $`2`
## $`1`
##
## $`2`
##
## $`3`
## $`1`
##
## $`2`
## A <3 x 1> GeneOverlapMatrix object
## Geneset A sizes:
## ME1 ME2 ME3
## 134 106 93
## Geneset B sizes:
## ZNF207
## 292
## ZNF207
## ME1 0.0000000
## ME2 0.4728693
## ME3 0.5401699
## ZNF207
## ME1 1.0090427
## ME2 0.5470847
Omix v1.0.0 – 2023-06-12 14:45:01
A report by Omix